Antimalarial activity and toxicity of Garcinia mangostana Linn.
نویسندگان
چکیده
منابع مشابه
Antimalarial activity of Garcinia mangostana L rind and its synergistic effect with artemisinin in vitro
BACKGROUND Malaria especially falciparum malaria still causes high morbidity and mortality in tropical countries. Several factors have been linked to this situation and the most important one is the rapid spread of parasite resistance to the currently available antimalarials, including artemisinin. Artemisinin is the main component of the currently recommended antimalarial, artemisinin based co...
متن کاملHypoglycaemic activity of ethanolic extract of Garcinia mangostana Linn. in normoglycaemic and streptozotocin-induced diabetic rats
BACKGROUND Various parts of Garcinia mangostana Linn., including its pericarp, have been traditionally used to treat a variety of ailments. In an attempt to establish its medicinal value, the present study was carried out to determine the hypoglycaemic potential of G. mangostana pericarp ethanolic extract (GME) using the streptozotocin-induced (STZ) diabetic rats. METHODS GME at 2,000 mg/kg w...
متن کاملAnti-inflammatory activity of mangostins from Garcinia mangostana.
The fruit hull of Garcinia mangostana Linn (Guttiferae) is used as an anti-inflammatory drug in Southeast Asia. Two xanthones, alpha- and gamma-mangostins, were isolated from the fruit hull of G. mangostana, and both significantly inhibited nitric oxide (NO) and PGE(2) production from lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. The IC(50) values for the inhibition of NO production by a...
متن کاملXanthones from the Pericarp of Garcinia mangostana.
Mangosteen (Garcinia mangostana L.) is one of the most popular tropical fruits (called the "Queen of Fruits"), and is a rich source of oxygenated and prenylated xanthone derivatives. In the present work, phytochemical investigation has resulted in one new prenylated xanthone and 13 known xanthones isolated from the pericarp of G. mangostana. Their structures were established by spectroscopic da...
متن کاملXanthones from the heartwood of Garcinia mangostana.
Twelve xanthones were isolated from the hexane extract of the heartwood of Garcinia mangostana from Myanmar. Their structures were determined using 1D and 2D NMR techniques
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Medicine
سال: 2014
ISSN: 1995-7645
DOI: 10.1016/s1995-7645(14)60118-8